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The mediating effects of quality of life, depression, and generalized anxiety on perceived barriers to employment success for people diagnosed with Neurofibromatosis Type 1.

Frank D BuonoMatthew E SprongErina PaulStaci MartinKaitlyn LarkinAmir Garakani
Published in: Orphanet journal of rare diseases (2021)
The current findings indicate that the barriers to successful employment for individuals with NF1 impact their quality of life, anxiety, and depression more than that of the matched controls. Poorer barriers of employment observed amongst people with a genetic disease can impact mental health and quality of life.
Keyphrases
  • mental health
  • mental illness
  • depressive symptoms
  • signaling pathway
  • physical activity
  • oxidative stress
  • social support
  • genome wide
  • gene expression
  • nuclear factor
  • immune response
  • pi k akt
  • dna methylation
  • copy number