miR-31-5p Regulates Type I Interferon by Targeting SLC15A4 in Plasmacytoid Dendritic Cells of Systemic Lupus Erythematosus.

Shifei LiQijun WuZhuyan JiangYaguang WuYuhong LiBing NiJun XiaoZhifang Zhai

Published in: Journal of inflammation research (2022)

miR-31-5p might involve in SLE pathogenesis through regulating IFN-I expression by negatively regulating SLC15A4 to increase the levels of IFN-α and ISGs in pDCs.

Keyphrases

dendritic cells
systemic lupus erythematosus
disease activity
immune response
regulatory t cells
poor prognosis
rheumatoid arthritis
binding protein