Glucocorticoid Dosages and Acute-Phase Reactant Levels at Giant Cell Arteritis Flare in a Randomized Trial of Tocilizumab.

John H StoneKatie TuckwellSophie DimonacoMicki KlearmanMartin AringerDaniel BlockmansElisabeth BrouwerMaria C CidBhaskar DasguptaJuergen RechCarlo SalvaraniHendrik Schulze-KoopsGeorg SchettRobert SpieraSebastian H UnizonyNeil Collinson

Published in: Arthritis & rheumatology (Hoboken, N.J.) (2019)

Most GCA flares occurred while patients were still receiving prednisone. Acute-phase reactant levels were not reliable indicators of flare in patients treated with TCZ plus prednisone or with prednisone alone. The addition of TCZ to prednisone facilitates earlier GCA control.

Keyphrases

giant cell
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
juvenile idiopathic arthritis
rheumatoid arthritis patients