Comprehensive transcriptomic analysis of heat shock proteins in the molecular subtypes of human breast cancer.
Felipe Carlos Martin ZoppinoMartin E Guerrero-GimenezGisela N CastroDaniel R CioccaPublished in: BMC cancer (2018)
We identified shared and specific HSP genes deregulated in BRCA subtypes. This study allowed the recognition of HSP genes not previously associated with BRCA and/or any cancer type, and the identification of three clinically relevant clusters based on HSPs expression patterns with influence on overall survival.
Keyphrases
- heat shock
- heat shock protein
- bioinformatics analysis
- heat stress
- genome wide
- endothelial cells
- papillary thyroid
- poor prognosis
- breast cancer risk
- oxidative stress
- genome wide identification
- induced pluripotent stem cells
- genome wide analysis
- squamous cell carcinoma
- dna methylation
- single molecule
- young adults
- lymph node metastasis