Prognostic value of CT-defined ground-glass opacity in early-stage lung adenocarcinomas: a single-center study and meta-analysis.
Jong Hyuk LeeYunhee ChoiHyunsook HongYoung Tae KimJin Mo GooHyung Jin KimPublished in: European radiology (2023)
• In a retrospective study of 612 patients with stage I lung adenocarcinoma, solid nodules were associated with shorter freedom from recurrence (adjusted hazard ratio [HR], 1.98; p = 0.01) and lung cancer-specific survival (adjusted HR, 1.937; p = 0.049). • Artificial intelligence-assessed solid nodules also showed worse prognosis (adjusted HR for freedom from recurrence, 1.94 [p = 0.01]; adjusted HR for lung cancer-specific survival, 1.93 [p = 0.04]). • In meta-analyses, the solid nodules were associated with shorter freedom from recurrence (HR, 2.45) and shorter overall survival (HR, 2.13).
Keyphrases
- free survival
- artificial intelligence
- early stage
- machine learning
- meta analyses
- systematic review
- big data
- deep learning
- magnetic resonance imaging
- randomized controlled trial
- squamous cell carcinoma
- radiation therapy
- contrast enhanced
- positron emission tomography
- sentinel lymph node
- image quality
- rectal cancer
- pet ct