Down-regulation of microsomal prostaglandin E2 synthase-1 in the infrapatellar fat pad of osteoarthritis patients with hypercholesterolemia.

Manabu MukaiKentaro UchidaShotaro TakanoDai IwaseJun AikawaGen InoueMasayuki MiyagiMasashi Takaso

Published in: Lipids in health and disease (2018)

mRNA levels of mPGES-1 are reduced in the IPFP of knee OA patients with HCE. Additional studies are need to clarify the effect of mPGES-1 down-regulation in OA pathology.

Keyphrases

knee osteoarthritis
total knee arthroplasty
adipose tissue
rheumatoid arthritis
cardiovascular events
cardiovascular disease
fatty acid