Uc.416 + A promotes epithelial-to-mesenchymal transition through miR-153 in renal cell carcinoma.

Yohei SekinoNaoya SakamotoKeisuke GotoRirino HonmaYoshinori ShigematsuThang Pham QuocKazuhiro SentaniNaohide OueJun TeishimaFumi KawakamiJose A KaramKanishka SircarAkio MatsubaraWataru Yasui

Published in: BMC cancer (2018)

The expression of Uc.416 + A was upregulated in RCC and especially in RCC tissues with sarcomatoid change. Uc.416 + A promoted epithelial-to-mesenchymal transition through miR-153. These results suggest that Uc.416 + A may be a promising therapeutic target.

Keyphrases

renal cell carcinoma
long non coding rna
cell proliferation
poor prognosis
long noncoding rna
gene expression
binding protein