PROMISE: a real-world clinical-genomic database to address knowledge gaps in prostate cancer.
Vadim S KoshkinVaibhav G PatelAlicia AliMehmet A BilenDeepak RavindranathanJoseph J ParkOlesia KelleziMarcin CieslikJustin ShayaAngelo CabalLandon C BrownMatthew LabriolaLaura S GrahamColin PritchardAbhishek TripathiSanober NusratPedro BarataAlbert JangShuang R ChenRohan GarjeLuna AcharyaClara HwangAmanda PillingWilliam K OhTomi JunDivya NatesanChris NguyenDeepak KilariMichael PierroBicky ThapaFrank CackowskiAlleda MackElisabeth I HeathCatherine H MarshallScott T TagawaSusan HalabiMichael T SchweizerAndrew J ArmstrongTanya Barauskas DorffAjjai AlvaRana R McKayPublished in: Prostate cancer and prostatic diseases (2021)
The PROMISE consortium provides a powerful clinical-genomic platform to interrogate and address data gaps that have arisen with increased genomic testing in the clinical management of prostate cancer. The dataset incorporates data from patient populations that are often underrepresented in clinical trials, generates new hypotheses to direct further research, and addresses important clinical questions that are otherwise difficult to investigate in prospective studies.