Association of Exosomal miR-34a with Markers of Dyslipidemia and Endothelial Dysfunction in Children and Adolescents with T1DM

Alshaymaa A. Ibrahim Aliaa A. Wahby Ingy Ashmawy Rehan M. Saleh Hend Mehawed Soliman

Published in: Journal of clinical research in pediatric endocrinology (2020)

This was the first study to show the altered expression of exosomal miR-34a among children and adolescents with T1DM. Moreover, association of miR-34a with markers of dyslipidemia and endothelial dysfunction was identified, suggesting that it could play a role in regulation of lipid metabolism and endothelial function in T1DM.

Keyphrases

long non coding rna
cell proliferation
long noncoding rna
poor prognosis
glycemic control
type diabetes
skeletal muscle
binding protein
weight loss