Role of Reduced Bdnf Expression in Novel Apc Mutant Allele-induced Intestinal and Colonic Tumorigenesis in Mice.

Ayşenur GokAynur IşikSinem BakirSarp UzunGunes GunerOzge OzcanBaris CerciIlyas OnbaşilarAytekin Akyol

Published in: In vivo (Athens, Greece) (2023)

Bdnf level has an important role in the Apc mutant intestinal and colonic tumorigenesis model. Modulation of Bdnf levels can be a potential therapeutic target in colorectal cancer.

Keyphrases

wild type
stress induced
poor prognosis
ulcerative colitis
high glucose
diabetic rats
high fat diet induced
binding protein
oxidative stress
climate change
metabolic syndrome