Identification of BGN and THBS2 as metastasis-specific biomarkers and poor survival key regulators in human colon cancer by integrated analysis.

Zhicheng HeJian LinCheng ChenYuanzhi ChenShuting YangXianghai CaiYingYing HeShubai Liu

Published in: Clinical and translational medicine (2022)

CRC metastatic progression, EMT phenotypic transition and poor survival time have been linked to BGN and THBS2. They could be utilized as potential diagnostic and therapeutic targets for colon cancer metastatic patients with a better prognosis.

Keyphrases

squamous cell carcinoma
small cell lung cancer
endothelial cells
free survival
epithelial mesenchymal transition
transcription factor
induced pluripotent stem cells
pluripotent stem cells
risk assessment
bioinformatics analysis