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Caring about Power Analyses.

Jennifer E MurrayScott T BarrettRebecca L BrockRick A Bevins
Published in: ACS chemical neuroscience (2017)
Everyone should care deeply about statistical power and effect size given that the current estimates of wasted nonreproducible and exaggerated research findings range from 50 to 85%, combined with the mandates from the National Institutes of Health (NIH) that proposal reviewers focus on scientific rigor and investigators consider sex as a biological variable. In this Viewpoint, we provide recommendations and resources regarding power analyses aimed at enhancing rigor, and hence decreasing waste, when designing experiments. As part of this effort, we also make recommendations for reporting key statistics that will aid others in estimating sample size based on published research.
Keyphrases
  • healthcare
  • quality improvement
  • clinical practice
  • public health
  • randomized controlled trial
  • heavy metals
  • adverse drug
  • systematic review
  • risk assessment
  • human health
  • climate change
  • life cycle