Impact of Diabetes on Myocardial Fibrosis in Patients With Hypertension: The REMODEL Study.

Chee Jian Pua Germaine LooMichelle KuiWai Lun Moy An-An Hii Vivian LeeChee-Tang ChinJennifer A Bryant Desiree-Faye Toh Chi-Hang Lee Stuart Alexander Cook Arthur Mark Richards Thu-Thao Le Calvin Woon-Loong Chin

Published in: Circulation. Cardiovascular imaging (2023)

Adverse cardiac remodeling was observed in patients with HTN/DM. The novel proteomic signatures and associated biological activities of increased immune and inflammatory response may partly explain these observations.

Keyphrases

inflammatory response
left ventricular
type diabetes
blood pressure
glycemic control
cardiovascular disease
lipopolysaccharide induced
genome wide
emergency department
heart failure
toll like receptor
metabolic syndrome
insulin resistance
adverse drug
gene expression
atrial fibrillation