Comparison of Effects of a Thrombin-Based Hemostatic Agent and Topical Tranexamic Acid on Blood Loss in Patients with Preexisting Thromboembolic Risk Undergoing a Minimally Invasive Total Knee Arthroplasty. A Prospective Randomized Controlled Trial.

Shih-Hsiang YenPo-Chun LinCheng-Ta WuJun-Wen Wang

Published in: BioMed research international (2021)

Our prospective randomized controlled study showed that intra-articular application of TXA was superior to hemostatic matrix (Floseal®) in terms of blood conservation in patients with preexisting thromboembolic risk undergoing minimally invasive TKA. This trial is registered with Clinicaltrials.gov (NCT02865174) on 08/09/2016.

Keyphrases

minimally invasive
total knee arthroplasty
randomized controlled trial
study protocol
phase iii
phase ii
total hip
clinical trial
atrial fibrillation
placebo controlled
meta analyses