Immune Contexture of MMR-Proficient Primary Colorectal Cancer and Matched Liver and Lung Metastases.

Maarit AhtiainenHanna ElomaaJuha P VäyrynenErkki-Ville WirtaTeijo KuopioOlli HelminenToni T SeppäläIlmo KellokumpuJukka-Pekka Mecklin

Published in: Cancers (2021)

Our study confirms the prognostic value of high ICS in least immune-infiltrated metastases in pMMR CRC patients. Major differences observed in immune contexture between primary tumours and metastases may have significance for treatment strategies for patients with advanced CRC.

Keyphrases

end stage renal disease
ejection fraction
chronic kidney disease
newly diagnosed
prognostic factors