Cross-Sectional Gene-Smoking Interaction Analysis in Relation to Subclinical Atherosclerosis-Results From the IMPROVE Study.

Buamina MaitusongFederica Laguzzi Rona Juliette Strawbridge Damiano Baldassarre Fabrizio Veglia Steve E Humphries Kai SavonenSudhir KurlMatteo PirroAndries J SmitPhilippe Giral Angela Silveira Elena TremoliAnders HamstenUlf de Faire Bruna Gigante Karin Leandernull null

Published in: Circulation. Genomic and precision medicine (2023)

Through nonhypothesis-driven analyses of gene-smoking interactions, several significant results were observed. These may stimulate further research on the role of specific genes in the process that determines the effect of smoking habits on the development of carotid atherosclerosis.

Keyphrases

genome wide
smoking cessation
genome wide identification
cross sectional
cardiovascular disease
copy number
dna methylation
transcription factor
type diabetes
gene expression
data analysis