PET/CT and inflammatory mediators in systemic sclerosis-associated interstitial lung disease.

Andréa L Bastos Gilda Aparecida Aparecida Ferreira Marcelo Mamede Eliane Viana Mancuzo Mauro Martins Texeira Flávia Patrícia Sena Teixeira Santos Cid S Ferreira Ricardo de Amorim Corrêa

Published in: Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia (2022)

18F-FDG PET/CT appears to be unable to differentiate the intensity of metabolic activity across HRCT patterns in chronic SSc patients. The association between CCL2 and GGO might be related to fibroblast activity in these areas; however, upregulated CCL2 expression in the lung tissue of SSc patients should be investigated in order to gain a better understanding of this association.

Keyphrases

systemic sclerosis
interstitial lung disease
end stage renal disease
pet ct
ejection fraction
newly diagnosed
prognostic factors
peritoneal dialysis
rheumatoid arthritis
poor prognosis
idiopathic pulmonary fibrosis
computed tomography
oxidative stress
positron emission tomography
liver fibrosis
patient reported