Quantitative assessment of p16 expression in FNA specimens from head and neck squamous cell carcinoma and correlation with HPV status.
Rita Abi-RaadManju L PrasadSyed M GilaniJames GarritanoDeborah BarlowGuoping CaiAdebowale J AdeniranPublished in: Cancer cytopathology (2020)
A cutoff of at least 40% p16 expression in tumor clusters may be appropriate for p16 positivity in cytology CB specimens. A positive HPV finding by PCR on needle rinse can be used as a substitute for p16 expression in surgical specimens.