Exogenous Thyroid Hormone Is Associated with Shortened Survival and Upregulation of High-Risk Gene Expression Profiles in Steroid Receptor-Positive Breast Cancers.
Reema S Wahdan-AlaswadSusan M EdgertonHiba SalemHyun Min KimAik Choon TanJessica Finlay-SchultzElizabeth A WellbergCarol A SartoriusBritta M JacobsenBryan R HaugenBolin LiuAnn D ThorPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2020)
We show clinically significant adverse interactions between THRT, estrogenic, and oncogenic signaling in patients with SR+ LN- breast cancer.