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Treatment of childhood disruptive behavior disorders and callous-unemotional traits: a systematic review and two multilevel meta-analyses.

Samantha PerlsteinMaddy FairEmily HongRebecca Waller
Published in: Journal of child psychology and psychiatry, and allied disciplines (2023)
DBD+CU children improve with treatment, but their greater DBD symptom severity requires specialized treatment modules that could be implemented alongside parenting programs. Conclusions are tempered by heterogeneity across studies and scant evidence from randomized controlled trials.
Keyphrases
  • randomized controlled trial
  • public health
  • young adults
  • clinical trial
  • combination therapy
  • dna methylation
  • replacement therapy
  • double blind