NP-12 peptide functionalized nanoparticles counteract the effect of bacterial lipopolysaccharide on cultured osteoblasts.
Manuel Toledano-OsorioElvira de Luna-BertosManuel ToledanoFrancisco Javier Manzano-MorenoConcepción RuizMariano SanzRaquel OsorioPublished in: Dental materials : official publication of the Academy of Dental Materials (2024)
TDg-NPs on titanium discs counteracted the detrimental effect of LPS by preventing the decrease on osteoblasts proliferation and mineralization, and produced an overexpression of proliferative and bone-promoting genes on human primary osteoblasts.
Keyphrases
- endothelial cells
- inflammatory response
- signaling pathway
- cell proliferation
- genome wide
- toll like receptor
- bone mineral density
- transcription factor
- quantum dots
- lps induced
- induced pluripotent stem cells
- pluripotent stem cells
- gene expression
- anti inflammatory
- immune response
- genome wide identification
- bone loss
- bone regeneration
- simultaneous determination
- genome wide analysis
- liquid chromatography