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Vulcan: Improved long-read mapping and structural variant calling via dual-mode alignment.

Yilei FuMedhat MahmoudViginesh Vaibhav MuraliramanFritz J SedlazeckTodd J Treangen
Published in: GigaScience (2022)
Vulcan is the first long-read mapping framework that combines two distinct gap penalty modes for improved structural variant recall and precision. Vulcan is open-source and available under the MIT License at https://gitlab.com/treangenlab/vulcan.
Keyphrases
  • high resolution
  • single molecule
  • high density