Intracranial Hemorrhage-Is Very Early Rehabilitation Safe? A Narrative Review.
Klaudia MarekEwa Zielinska-NowakJustyna RedlickaMichał StarostaElżbieta Dorota MillerPublished in: Journal of clinical medicine (2024)
Intracerebral hemorrhage (ICH) is a serious neurological disease with a 30-day mortality rate of 34-50%. Rehabilitation can reduce disability and improve recovery from a stroke; however, it is uncertain whether early rehabilitation is safe. There are many studies and reviews on rehabilitation for chronic conditions, but there is not enough information on the details of rehabilitation in the acute and subacute phases of ICH. We analyzed clinical trials from the electronic databases PubMed, PubMedCentral, Medline, Cochrane Library, Embase, Scopus and PEDro. Based on the data, we determined that early rehabilitation of patients with ICH has beneficial effects on improving ADL scores, motor function, functional independence, quality of life, improved gait, improved trunk control and reduced mortality. Varying the duration and intensity of rehabilitation in patients with ICH may improve health status, functional outcomes and reduce the length of stay in the hospital. The earliest protocol for initiating rehabilitation after ICH included up to 24 h after stroke onset. The medical literature indicates the need for more randomized controlled group trials of early rehabilitation in patients with acute and subacute ICH with a precise timing of rehabilitation initiation. This narrative review aims to summarize the existing evidence and provide insights into the current state of knowledge regarding the safety of early rehabilitation. There is a need for a clear definition of "early rehabilitation" when determining the most appropriate time to begin rehabilitation therapy.
Keyphrases
- clinical trial
- healthcare
- systematic review
- randomized controlled trial
- stem cells
- cardiovascular disease
- cardiovascular events
- type diabetes
- multiple sclerosis
- big data
- bone marrow
- liver failure
- deep learning
- open label
- optical coherence tomography
- risk factors
- subarachnoid hemorrhage
- study protocol
- double blind
- hepatitis b virus
- phase ii
- electronic health record
- smoking cessation
- acute respiratory distress syndrome
- artificial intelligence
- acute care
- placebo controlled