Low Prevalence of the Four Common Colombian Founder Mutations in BRCA1 and BRCA2 in Early-Onset and Familial Afro-Colombian Patients with Breast Cancer.
Elizabeth VargasDiana Maria Torres LopezRobert de DeugdFabian GilAlejandra NovaLina MoraLuis Fernando ViañaJosé David HernandezRicardo BrugesUte HamannPublished in: The oncologist (2018)
Risk reduction intervention programs are needed for women who are found to carry a BRCA1/2 mutation, as is the implementation of prevention programs for patients with inherited breast cancer, to reduce the burden of inherited diseases. With the aim of reducing racial disparities in breast cancer prevention, this study focused on genetic testing and treatment for patients in a minority population with BRCA1/2 mutations.
Keyphrases
- breast cancer risk
- early onset
- end stage renal disease
- late onset
- randomized controlled trial
- ejection fraction
- newly diagnosed
- chronic kidney disease
- risk factors
- primary care
- healthcare
- peritoneal dialysis
- prognostic factors
- type diabetes
- patient reported outcomes
- adipose tissue
- metabolic syndrome
- african american
- insulin resistance
- combination therapy
- replacement therapy
- pregnancy outcomes