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Extracellular vesicles-coupled miRNAs from oviduct and uterus modulate signaling pathways related to lipid metabolism and bovine early embryo development.

Rosane MazzarellaKarina Cañón-BeltránYulia N CajasMeriem HamdiEncina M GonzálezJuliano C da SilveiraClaudia L V LealDimitrios Rizos
Published in: Journal of animal science and biotechnology (2024)
Our study suggests that miRNAs within OF- and UF-EVs could modulate bovine embryo development and quality, providing insights into the intricate maternal-embryonic communication that might be involved in modulating lipid metabolism, immune response, and implantation during early pregnancy.
Keyphrases
  • immune response
  • signaling pathway
  • pregnancy outcomes
  • fatty acid
  • pi k akt
  • physical activity
  • cell proliferation
  • drug induced
  • endoplasmic reticulum stress
  • preterm birth