Respiratory pathogens associated with intubated pediatric patients following hematopoietic cell transplant.
Shira J GertzJennifer McArthurDeyin D HsingMara E NituLincoln S SmithAshley LoomisJulie C FitzgeraldChristine N DuncanKris M MahadeoJerelyn MoffetMark W HallEmily L PinosIra M CheifetzCourtney M Rowannull nullPublished in: Transplant infectious disease : an official journal of the Transplantation Society (2020)
In this multicenter retrospective cohort of intubated pediatric post-HCT patients, there was high variability in the respiratory pathogens identified. Type of pathogen and method of detection did not affect PICU mortality. The presence of any organism leads to increased PICU mortality, longer PICU stay, and increased duration of mechanical ventilation suggesting that early detection and treatment of pathogens may be beneficial in this population.
Keyphrases
- mechanical ventilation
- gram negative
- end stage renal disease
- cardiovascular events
- acute respiratory distress syndrome
- antimicrobial resistance
- ejection fraction
- chronic kidney disease
- intensive care unit
- newly diagnosed
- risk factors
- bone marrow
- cross sectional
- single cell
- prognostic factors
- peritoneal dialysis
- clinical trial
- cardiovascular disease
- cell therapy
- extracorporeal membrane oxygenation
- mesenchymal stem cells
- candida albicans
- young adults
- coronary artery disease
- replacement therapy
- smoking cessation
- real time pcr