BRAF-induced EHF expression affects TERT in aggressive papillary thyroid cancer.

Yiyi XuJiwei GaoNa WangJan ZedeniusInga-Lena NilssonWeng-Onn LuiDawei XuC Christofer JuhlinCatharina Larsson Ninni Mu

Published in: The Journal of clinical endocrinology and metabolism (2024)

The ETS transcription factor EHF is associated with poor prognosis in PTC. This is potentially mediated by BRAF-induced upregulation of EHF which in turn increases TERT expression in TERT promoter mutated cells.

Keyphrases

poor prognosis
transcription factor
long non coding rna
diabetic rats
induced apoptosis
drug induced
dna methylation
gene expression
wild type
signaling pathway
metastatic colorectal cancer
sensitive detection
single molecule