Dietary AhR Ligands Have No Anti-Fibrotic Properties in TGF-β1-Stimulated Human Colonic Fibroblasts.
Asma AmamouLinda YakerMathilde LeboutteChristine Bôle-FeysotGuillaume SavoyeRachel Marion-LetellierPublished in: Nutrients (2022)
Our data highlight that none of the tested dietary AhR ligands had an effect on fibrosis markers in TGF-β1-stimulated human colonic fibroblast cells in our experimental conditions. Further studies are now required to identify novel potential targets in intestinal fibrosis.
Keyphrases
- endothelial cells
- transforming growth factor
- induced apoptosis
- induced pluripotent stem cells
- pluripotent stem cells
- systemic sclerosis
- oxidative stress
- cell death
- cell proliferation
- machine learning
- epithelial mesenchymal transition
- idiopathic pulmonary fibrosis
- signaling pathway
- human health
- artificial intelligence
- deep learning