Negative regulators of Wnt signaling pathway SFRP1 and SFRP3 expression in preterm and term pathologic placentas.

Jasenka Zmijanac PartlValentina KarinAnita SkrticTamara Nikuseva-MarticAlan SermanJelena MlinarecMirna Curkovic-PericaSemir Vranic Ljiljana Serman

Published in: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians (2017)

Our findings indicate the active involvement of negative Wnt regulators SFRP1/SFRP3 in placental development and important role in pathology of pregnancy.

Keyphrases

signaling pathway
cell proliferation
preterm birth
stem cells
transcription factor
poor prognosis
gestational age
preterm infants
neoadjuvant chemotherapy
pi k akt
low birth weight
pregnant women
locally advanced
pregnancy outcomes
lymph node