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Concomitant intraperitoneal and systemic chemotherapy for extensive peritoneal metastases of colorectal origin: protocol of the multicentre, open-label, phase I, dose-escalation INTERACT trial.

Nadine Leonie de BoerAlexandra R M Brandt-KerkhofEva V E MadsenMarjolein DiepeveenEsther van MeertenRuben A G van EerdenFemke M de ManRachida BouamarStijn L W KoolenIgnace H J T de HinghChecca BakkersKoen P RoversGeert-Jan M CreemersMaarten J DeenenOnno W KranenburgAlexander ConstantinidesRon H J MathijssenCornelis VerhoefJacobus W A Burgernull nullnull null
Published in: BMJ open (2019)
NL6988 and NL2018-000479-33; Pre-results.
Keyphrases
  • open label
  • study protocol
  • phase iii
  • phase ii
  • randomized controlled trial
  • clinical trial
  • phase ii study
  • locally advanced
  • double blind
  • squamous cell carcinoma
  • radiation therapy