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Effects of Histidine and Sucrose on the Biophysical Properties of a Monoclonal Antibody.

Youngbin BaekNripen SinghAbhiram ArunkumarAndrew L Zydney
Published in: Pharmaceutical research (2016)
These results provide important insights into the effects of both histidine and sucrose on the behavior of concentrated mAb solutions, including the potential impact on ultrafiltration / diafiltration processes.
Keyphrases
  • monoclonal antibody