Andrew L Zydney (Andrew Zydney)

ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 59

Top Venues

Biotechnology progress

Biotechnology and bioengineering

Membranes

Biotechnology journal

Pennsylvania State University

Massachusetts Institute of Technology (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Pennsylvania State University Jan 01 2002

United States

Bayard D. Kunkle Chair :: Chemical Engineering

Education History

Massachusetts Institute of Technology Sep 01 1980 - Jan 31 1985

United States

PHD :: Chemical Engineering

Yale University Sep 01 1976 - May 15 1980

United States

BSC :: Chemical Engineering

Publications

Mohammad A Afzal, Joshua Peles, Andrew L Zydney
Comparative Analysis of the Impact of Protein on Virus Retention for Different Virus Removal Filters. Membranes 14 (7) (2024)
Ali Behboudi, Mirko Minervini, Zachary S Badinger, William W Haddad, Andrew L Zydney
Addition of sodium malonate alters the morphology and increases the critical flux during tangential flow filtration of precipitated immunoglobulins. Protein science : a publication of the Protein Society 33 (6) (2024)
Aylin Mohammadzadehmarandi, Andrew L Zydney
Buffer effects on protein sieving losses in ultrafiltration and their relationship to biophysical properties. Biotechnology progress (2024)
Mohammad A Afzal, Joshua Peles, Andrew L Zydney
Comparative Analysis of the Impact of Protein on Virus Retention for Different Virus Removal Filters. Membranes 14 (7) (2024)
Ali Behboudi, Mirko Minervini, Zachary S Badinger, William W Haddad, Andrew L Zydney
Addition of sodium malonate alters the morphology and increases the critical flux during tangential flow filtration of precipitated immunoglobulins. Protein science : a publication of the Protein Society 33 (6) (2024)
Zhuoshi Du, Siyi Qiu, Kanwal Gill, Vishal Toprani, Andrew L Zydney
Filtration of a multi-serotype glycoconjugate vaccine drug product through sterilizing grade 0.2/0.22 µm pore size filters. Biotechnology journal 19 (2) (2024)
Mohammad A Afzal, Joshua Peles, Andrew L Zydney
Comparative Analysis of the Impact of Protein on Virus Retention for Different Virus Removal Filters. Membranes 14 (7) (2024)
Jiwon Na, Ali Behboudi, Jiwon Mun, Hoeun Jin, Andrew L Zydney, Youngbin Baek
Protein loss during membrane processes in biopharmaceutical manufacturing. Biotechnology journal 19 (5) (2024)
Da Zhang, Sumith Ranil Wickramasinghe, Andrew L Zydney, John P Smelko, Abdullah Loman, April Wheeler, Xianghong Qian
Proteomic analysis of host cell protein fouling during bioreactor harvesting. Biotechnology progress 40 (4) (2024)
Da Zhang, Sumith Ranil Wickramasinghe, Andrew L Zydney, John P Smelko, Abdullah Loman, April Wheeler, Xianghong Qian
Proteomic analysis of host cell protein fouling during bioreactor harvesting. Biotechnology progress (2024)
Joshua Peles, Benjamin Cacace, Christina Carbrello, Sal Giglia, Andrew L Zydney
Protein fouling during constant-flux virus filtration: Mechanisms and modeling. Biotechnology and bioengineering (2023)
Zhuoshi Du, Kanwal Gill, Vishal Toprani, Andrew L Zydney
Sterile Filtration of a Multi-Serotype Glycoconjugate Vaccine Drug Product. Biotechnology and bioengineering (2023)
Mirko Minervini, Matthew Mergy, Yuncan Zhu, Mario A Gutierrez Diaz, Craig Pointer, Oleg Shinkazh, Sheldon F Oppenheim, Steven M Cramer, Todd M Przybycien, Andrew L Zydney
Continuous precipitation-filtration process for initial capture of a monoclonal antibody product using a four-stage countercurrent hollow fiber membrane washing step. Biotechnology and bioengineering (2023)
Zhuoshi Du, Kanwaldeep Gill, Vishal Toprani, Andrew L Zydney
Sterile filtration of a multi-serotype glycoconjugate vaccine drug product. Biotechnology and bioengineering (2023)
Mohammad A Afzal, Andrew L Zydney
Impact of proteins and protein fouling on virus retention during virus removal filtration. Biotechnology and bioengineering (2023)
Akshay S Chaubal, Andrew L Zydney
Single-Pass Tangential Flow Filtration (SPTFF) of Nanoparticles: Achieving Sustainable Operation with Dilute Colloidal Suspensions for Gene Therapy Applications. Membranes 13 (4) (2023)
Matthew Billups, Mirko Minervini, Melissa Holstein, Hasin Feroz, Swarnim Ranjan, Jessica Hung, Andrew L Zydney
The role of intermolecular interactions on monoclonal antibody filtration through virus removal membranes. Biotechnology journal (2023)
Akshay S Chaubal, Andrew L Zydney
Single-Pass Tangential Flow Filtration (SPTFF) of Nanoparticles: Achieving Sustainable Operation with Dilute Colloidal Suspensions for Gene Therapy Applications. Membranes 13 (4) (2023)
Aylin Mohammadzadehmarandi, Amy Determan, Christian Krumm, Lucas D McIntosh, Andrew L Zydney
High-performance countercurrent membrane purification for host cell protein removal from monoclonal antibody products. Biotechnology and bioengineering (2023)
Vikram Sundar, Da Zhang, Xianghong Qian, Ranil Wickramasinghe, John Paul Smelko, Christina Carbrello, Yara Jabbour Al Maalouf, Andrew L Zydney
Use of SEM and Energy Dispersive X-ray Spectroscopy to Identify Key Fouling Species during Alternating Tangential Filtration. Biotechnology progress (2023)
Liang-Kai Chu, Ehsan Espah Borujeni, Xuankuo Xu, Sanchayita Ghose, Andrew L Zydney
Comparison of host cell protein removal by depth filters with diatomaceous earth and synthetic silica filter aids using model proteins. Biotechnology and bioengineering (2023)
Akshay S Chaubal, Andrew L Zydney
Single-Pass Tangential Flow Filtration (SPTFF) of Nanoparticles: Achieving Sustainable Operation with Dilute Colloidal Suspensions for Gene Therapy Applications. Membranes 13 (4) (2023)
Patrick Romann, Philip Giller, Antony Sibilia, Christoph Herwig, Andrew L Zydney, Arnaud Perilleux, Jonathan Souquet, Jean-Marc Bielser, Thomas K Villiger
Co-current filtrate flow in TFF perfusion processes: Decoupling transmembrane pressure from crossflow to improve product sieving. Biotechnology and bioengineering (2023)
Vikram Sundar, Da Zhang, Xianghong Qian, S Ranil Wickramasinghe, John Paul Smelko, Christina Carbrello, Yara Jabbour Al Maalouf, Andrew L Zydney
Use of scanning electron microscopy and energy dispersive X-ray spectroscopy to identify key fouling species during alternating tangential filtration. Biotechnology progress (2023)
Akshay S Chaubal, Andrew L Zydney
Single-Pass Tangential Flow Filtration (SPTFF) of Nanoparticles: Achieving Sustainable Operation with Dilute Colloidal Suspensions for Gene Therapy Applications. Membranes 13 (4) (2023)
Zhuoshi Du, Seyed Pouria Motevalian, Brenda Carrillo Conde, Kelvin Reilly, Andrew L Zydney
Scale-up issues during sterile filtration of glycoconjugate vaccines. Biotechnology progress 38 (4) (2022)
Liang-Kai Chu, S Ranil Wickramasinghe, Xianghong Qian, Andrew L Zydney
Retention and Fouling during Nanoparticle Filtration: Implications for Membrane Purification of Biotherapeutics. Membranes 12 (3) (2022)
Negin Nejatishahidein, Minyoung Kim, Seon Yeop Jung, Ehsan E Borujeni, Lara Fernandez-Cerezo, David J Roush, Ali Borhan, Andrew L Zydney
Scale-up issues for commercial depth filters in bioprocessing. Biotechnology and bioengineering 119 (4) (2022)
Solomon Isu, Xianghong Qian, Andrew L Zydney, Sumith Ranil Wickramasinghe
Process- and Product-Related Foulants in Virus Filtration. Bioengineering (Basel, Switzerland) 9 (4) (2022)
Neil Taylor, Wanli Ma, Adam Kristopeit, Sheng-Ching Wang, Andrew L Zydney
Evaluating Nanoparticle Hydrophobicity Using Analytical Membrane Hydrophobic Interaction Chromatography. Analytical chemistry 94 (24) (2022)
Matthew Billups, Mirko Minervini, Melissa Holstein, Hasin Feroz, Swarnim Ranjan, Jessica Hung, Haiying Bao, Zheng Jian Li, Sanchayita Ghose, Andrew L Zydney
Role of membrane structure on the filtrate flux during monoclonal antibody filtration through virus retentive membranes. Biotechnology progress 38 (2) (2022)
Kevork Oliver Messerian, Anton Zverev, Jack F Kramarczyk, Andrew L Zydney
Pressure-dependent fouling behavior during sterile filtration of mRNA-containing lipid nanoparticles. Biotechnology and bioengineering 119 (11) (2022)
Mohammad A Afzal, Andrew L Zydney
Effect of filtrate flux and process disruptions on virus retention by a relatively homogeneous virus removal membrane. Biotechnology progress 38 (4) (2022)
Anna Malakian, Seon Yeop Jung, Mohammad A Afzal, Christina Carbrello, Sal Giglia, Matthew Johnson, Corinne Miller, William Rayfield, Dave Boenitz, David Cetlin, Andrew L Zydney
Development of a transient inline spiking system for evaluating virus clearance in continuous bioprocessing-Proof of concept for virus filtration. Biotechnology and bioengineering 119 (8) (2022)
Parinaz Emami, Fatemeh Fallahianbijan, Erica Dinse, Seyed Pouria Motevalian, Brenda Carrillo Conde, Kelvin Reilly, Andrew L Zydney
Fouling Behavior during Sterile Filtration of Different Glycoconjugate Serotypes Used in Conjugate Vaccines. Pharmaceutical research 38 (1) (2021)
Tyler E Culp, Biswajit Khara, Kaitlyn P Brickey, Michael Geitner, Tawanda J Zimudzi, Jeffrey D Wilbur, Steven D Jons, Abhishek Roy, Mou Paul, Baskar Ganapathysubramanian, Andrew L Zydney, Manish Kumar, Enrique D Gomez
Nanoscale control of internal inhomogeneity enhances water transport in desalination membranes. Science (New York, N.Y.) 371 (6524) (2021)
Christopher J Yehl, Andrew L Zydney
Analysis of tradeoffs between purification factor and yield for high-performance countercurrent membrane purification for protein separations. Biotechnology progress (2021)
Zhuoshi Du, Seyed Pouria Motevalian, Brenda Carillo-Conde, Kelvin Reilly, Andrew L Zydney
Prefiltration enhances performance of sterile filtration for glycoconjugate vaccines. Biotechnology progress 37 (5) (2021)
Neil Taylor, Wanli Ma, Adam Kristopeit, Sheng-Ching Wang, Andrew L Zydney
Evaluation of a sterile filtration process for viral vaccines using a model nanoparticle suspension. Biotechnology and bioengineering 118 (1) (2020)
Zhao Li, Ting-Hsi Chen, Erha Andini, Jonathan L Coffman, Todd M Przybycien, Andrew L Zydney
Enhanced filtration performance using feed-and-bleed configuration for purification of antibody precipitates. Biotechnology progress 37 (1) (2020)
Ivan Manzano, Neil Taylor, Matthew Csordas, Grace E Vezeau, Howard M Salis, Andrew L Zydney
Purification of Cas9-RNA complexes by ultrafiltration. Biotechnology progress 37 (2) (2020)
Mario G Jabra, Yinying Tao, John F Moomaw, Zhao Yu, Brian J Hotovec, Steven B Geng, Andrew L Zydney
pH and excipient profiles during formulation of highly concentrated biotherapeutics using bufferless media. Biotechnology and bioengineering 117 (11) (2020)
Qin Gu, Zhao Li, Jonathan L Coffman, Todd M Przybycien, Andrew L Zydney
High throughput solubility and redissolution screening for antibody purification via combined PEG and zinc chloride precipitation. Biotechnology progress 36 (6) (2020)
Negin Nejatishahidein, Ehsan E Borujeni, David J Roush, Andrew L Zydney
Effectiveness of host cell protein removal using depth filtration with a filter containing diatomaceous earth. Biotechnology progress 36 (6) (2020)
Youngbin Baek, Parinaz Emami, Nripen Singh, Andrew Ilott, Erinc Sahin, Andrew L Zydney
Stereospecific interactions between histidine and monoclonal antibodies. Biotechnology and bioengineering 116 (10) (2019)
Hadi Nazem-Bokaee, Dayue Chen, Sean Michael O'Donnell, Andrew L Zydney
New insights into the performance characteristics of the Planova-series hollow-fiber parvovirus filters using confocal and electron microscopy. Biotechnology and bioengineering 116 (8) (2019)
Dmitriy Fedorenko, Amit K Dutta, Jasmine Tan, Jonathan Walko, Mark Brower, Nuno D S Pinto, Andrew L Zydney, Oleg Shinkazh
Improved protein A resin for antibody capture in a continuous countercurrent tangential chromatography system. Biotechnology and bioengineering 117 (3) (2019)
Zhao Li, Qin Gu, Jonathan L Coffman, Todd Przybycien, Andrew L Zydney
Continuous precipitation for monoclonal antibody capture using countercurrent washing by microfiltration. Biotechnology progress 35 (6) (2019)
Mario G Jabra, Christopher J Yehl, Andrew L Zydney
Multistage continuous countercurrent diafiltration for formulation of monoclonal antibodies. Biotechnology progress 35 (4) (2019)
Fatemeh Fallahianbijan, Sal Giglia, Christina Carbrello, David Bell, Andrew L Zydney
Impact of protein fouling on nanoparticle capture within the Viresolve® Pro and Viresolve® NFP virus removal membranes. Biotechnology and bioengineering 116 (9) (2019)
Ying Li, Ivan Manzano, Andrew L Zydney
Effects of polyamines on the ultrafiltration of plasmid DNA. Biotechnology progress 35 (2) (2018)
Christopher J Yehl, Mario G Jabra, Andrew L Zydney
Hollow fiber countercurrent dialysis for continuous buffer exchange of high-value biotherapeutics. Biotechnology progress 35 (2) (2018)
Parinaz Emami, Seyed Pouria Motevalian, Erin Pepin, Andrew L Zydney
Purification of a conjugated polysaccharide vaccine using tangential flow diafiltration. Biotechnology and bioengineering 116 (3) (2018)
Tae Ryung Kim, Mahsa Hadidi, Seyed Pouria Motevalian, Takashi Sunohara, Andrew L Zydney
Effects of Plasma Proteins on the Transport and Surface Characteristics of Polysulfone/Polyethersulfone and Asymmetric Cellulose Triacetate High Flux Dialyzers. Artificial organs 42 (11) (2018)
Youngbin Baek, Nripen Singh, Abhiram Arunkumar, Michael Borys, Zheng-Jian Li, Andrew L Zydney
Ultrafiltration behavior of monoclonal antibodies and Fc-fusion proteins: Effects of physical properties. Biotechnology and bioengineering 114 (9) (2017)
Youngbin Baek, Deyu Yang, Nripen Singh, Abhiram Arunkumar, Sanchayita Ghose, Zheng Jian Li, Andrew L Zydney
pH variations during diafiltration due to buffer nonidealities. Biotechnology progress 33 (6) (2017)
Zhao Li, Andrew L Zydney
Effect of zinc chloride and PEG concentrations on the critical flux during tangential flow microfiltration of BSA precipitates. Biotechnology progress 33 (6) (2017)
Anirudh M K Nambiar, Ying Li, Andrew L Zydney
Countercurrent staged diafiltration for formulation of high value proteins. Biotechnology and bioengineering 115 (1) (2017)
Youngbin Baek, Nripen Singh, Abhiram Arunkumar, Andrew L Zydney
Effects of Histidine and Sucrose on the Biophysical Properties of a Monoclonal Antibody. Pharmaceutical research 34 (3) (2016)

Andrew L Zydney.css-eqlu8i{font-size:small;padding-left:4px;} (Andrew Zydney)

Publication Activity (10 Years)

Top Topics

Top Venues

Andrew L Zydney (Andrew Zydney)