A three-component difunctionalization of N -alkenyl amides via organophotoredox radical-polar crossover.

Herein, we report a three-component organophotoredox coupling of N -alkenyl amides with α-bromocarbonyls and various nucleophiles. This transition metal-free difunctionalization protocol installs sequential C-C and C-Y (Y = S/O/N) bonds in alkenes. This reaction works with terminal and internal alkenes containing both cyclic and acyclic amides via radical-polar crossover.