Hydrocortisone-associated death and hospital length of stay in patients with sepsis: A retrospective cohort of large-scale clinical care data.

Mohan LiRaymond NoordamElizabeth M WinterMatijs van MeursHjalmar R BoumaM Sesmu ArbousPatrick C N RensenSander Kooijman

Published in: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie (2023)

Hydrocortisone treatment is associated with increased risk of death as well as prolonged hospital stay in septic patients. Although residual confounding (by indication) cannot be ruled out completely due to the observational nature of the study, the present study suggests clinical implication of hydrocortisone use in patients with sepsis.

Keyphrases

septic shock
healthcare
acute kidney injury
end stage renal disease
intensive care unit
palliative care
peritoneal dialysis
emergency department
prognostic factors
cross sectional
acute care
quality improvement
pain management
patient reported outcomes