Login / Signup

Epigenetic Role of Histone Lysine Methyltransferase and Demethylase on the Expression of Transcription Factors Associated with the Epithelial-to-Mesenchymal Transition of Lung Adenocarcinoma Metastasis to the Brain.

Young Min LeeSeok Hyun KimMinseok S KimDae Cheol KimEun Hee LeeJu Suk LeeSung-Hun LeeYoung Zoon Kim
Published in: Cancers (2020)
The results suggest that certain histone lysine methyltransferase/demethylase, such as MLL4, UTX, and EZH2, regulate the expression of EMT-TFs such as Slug, ZEB1, and Twist epigenetically, which may thereby influence cancer metastasis from the lung to the brain.
Keyphrases