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Intravitreal ranibizumab versus aflibercept following treat and extend protocol for neovascular age-related macular degeneration.

Alaa Din AbdinShady SuffoFatima AsiAchim LangenbucherBerthold Seitz
Published in: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie (2019)
Significant differences regarding BCVA, central macular thickness, and the number of injections were not found between aflibercept and ranibizumab during the first year following the treat and extend protocol. However, the significantly higher major recurrence rates in the aflibercept group after extending the treatment interval to 10 weeks might suggest that aflibercept should better not to be used in longer than 8 weeks intervals during the first year of treatment.
Keyphrases
  • age related macular degeneration
  • randomized controlled trial
  • optical coherence tomography
  • gestational age
  • replacement therapy
  • free survival
  • smoking cessation