Surgical Treatment for Isolated Tricuspid Valve Disease: A Less Invasive Approach for Better Outcomes.
Cristina BarberoMarco PocarDario BrennaAndrea CostamagnaValentina AloiCecilia CapozzaClaudia FilippiniAnna Chiara TrompeoStefano SalizzoniLuca BrazziMauro RinaldiPublished in: Journal of clinical medicine (2024)
Background . Severe tricuspid valve (TV) disease has a strong association with right ventricle dysfunction, heart failure and mortality. Nevertheless, surgical indications for isolated TV disease are still uncommon. The purpose of this study is to analyze outcomes of patients undergoing minimally invasive isolated TV surgery (ITVS). Methods . Data of patients undergoing right mini-thoracotomy ITVS were prospectively collected. A subgroup analysis was performed on late referral patients. Five-year survival was assessed using the Kaplan-Meier survival estimate. Results . Eighty-one consecutive patients were enrolled; late referral was recorded in 8 out of 81 (9.9%). No cases of major vascular complications nor of stroke were reported. A 30-day mortality was reported in one patient (1.2%). Five-year Kaplan-Meier survival analysis revealed a significant difference between late referral patients and the control group ( p = 0.01); late referral and Euroscore II were found to be significantly associated with reduced mid-term survival ( p = 0.005 and p = 0.01, respectively). Conclusions . To date, perioperative mortality in patients undergoing ITVS is still consistently high, even in high-volume, high-experienced centres, and this accounts for the low rate of referral. Results from our report show that, with proper multidisciplinary management, appropriate pre-operative screening, and allocation to the safest approach, ITVS may offer better results than expected.
Keyphrases
- patients undergoing
- end stage renal disease
- minimally invasive
- heart failure
- newly diagnosed
- mitral valve
- primary care
- ejection fraction
- chronic kidney disease
- peritoneal dialysis
- prognostic factors
- atrial fibrillation
- risk factors
- cardiovascular events
- oxidative stress
- clinical trial
- acute kidney injury
- randomized controlled trial
- coronary artery
- type diabetes
- metabolic syndrome
- coronary artery disease
- machine learning
- big data
- pulmonary hypertension
- left ventricular
- free survival
- artificial intelligence
- blood brain barrier
- insulin resistance
- data analysis
- cerebral ischemia