Prognostic Value of Programmed Death Ligand-1 Expression in Solid Tumors Irrespective of Immunotherapy Exposure: A Systematic Review and Meta-Analysis.
Ramy R SalehJordan L ScottNicholas MetiDanielle PerlonRouhi FazelzadAlberto OcanaEitan AmirPublished in: Molecular diagnosis & therapy (2022)
High expression of PD-L1 is associated with worse survival in solid tumors albeit with significant heterogeneity among tumor types. The effect is consistent in early-stage and metastatic disease and is not sensitive to method of PD-L1 quantification. These data can provide additional information for the counseling of patients with cancer about prognosis.