The correlation between baseline score and post-intervention score, and its implications for statistical analysis.
Lei CliftonDavid A CliftonPublished in: Trials (2019)
The correlation between baseline and post-intervention scores can be derived using the variance sum law. We can then use the derived correlation to calculate the required sample size in the design stage. Baseline imbalance may occur in RCTs, and ANCOVA should be used to adjust for baseline in the analysis stage.
Keyphrases