Tramadol for management of fibromyalgia pain and symptoms: Systematic review.

Aline Pereira da Rocha Carolina Christianini Mizzaci Ana Carolina Pereira Nunes Pinto Aléxia Gabriela da Silva Vieira Vinicius Tassoni Civile Virgínia Fernandes Moça Trevisani

Published in: International journal of clinical practice (2019)

This systematic review found a dearth of clinical trials on tramadol in patients with fibromyalgia. Although the combination of monoamine and opioid mechanism of tramadol has shown positive effects for fibromyalgia, the available evidence is not sufficient to support or refute the use of tramadol in clinical practice for pain or symptom management. Protocol registration number in the PROSPERO database: CRD42017062139.

Keyphrases

systematic review
chronic pain
pain management
meta analyses
clinical trial
clinical practice
randomized controlled trial
emergency department
postoperative pain
open label
adverse drug
patient reported
double blind