Effects of Dexmedetomidine on Immunomodulation and Pain Control in Videolaparoscopic Cholecystectomies: A Randomized, Two-Arm, Double-Blinded, Placebo-Controlled Trial.

Gustavo Nascimento SilvaVirna Guedes BrandãoMarcelo Vaz PerezKai-Uwe LewandrowskiRossano Kepler Alvim Fiorelli

Published in: Journal of personalized medicine (2023)

Dexmedetomidine decreased interleukin-6 4-6 h after surgery, likely by providing a sympatholytic effect. It provides good perioperative analgesia without respiratory depression. Implementing dexmedetomidine during laparoscopic cholecystectomy has a good safety profile and may lower healthcare expenditure due to faster postoperative recovery.

Keyphrases

cardiac surgery
healthcare
pain management
patients undergoing
acute kidney injury
chronic pain
depressive symptoms
neuropathic pain
randomized controlled trial
quality improvement
study protocol
physical activity
ultrasound guided
clinical trial
spinal cord injury
spinal cord
health information