Macrophages Phenotype Regulated by IL-6 Are Associated with the Prognosis of Platinum-Resistant Serous Ovarian Cancer: Integrated Analysis of Clinical Trial and Omics.

Xiaoqing Wu Wenping Lu Chaojie Xu Cuihong Jiang Zhili Zhuo Ruipeng Wang Dongni Zhang Yongjia Cui Lei Chang Xi Zuo Ya'nan WangHeting MeiWeixuan ZhangMengfan ZhangChen Li

Published in: Journal of immunology research (2023)

Thus, the macrophage phenotype is a prognostic indicator in PROC patients, possibly via a hyperactive IL-6-related pathway, providing an additional clue for the therapeutic intervention of PROC.

Keyphrases

clinical trial
end stage renal disease
newly diagnosed
randomized controlled trial
chronic kidney disease
ejection fraction
high grade
prognostic factors
single cell
peritoneal dialysis
phase ii
double blind