Nicorandil mitigates arsenic trioxide-induced lung injury via modulating vital signalling pathways SIRT1/PGC-1α/TFAM, JAK1/STAT3, and miRNA-132 expression.
Basel A Abdel-WahabDalia ZafaarMohammed Shafiuddin HabeebEhab A M El-ShouraPublished in: British journal of pharmacology (2024)
The results presented here show nicorandil as a significant agent in attenuating lung injury induced by ATO in a rodent model. Nonetheless, further clinical studies are warranted to strengthen these findings.