Wnt1 Promotes EAAT2 Expression and Mediates the Protective Effects of Astrocytes on Dopaminergic Cells in Parkinson's Disease.

Lei Wei Chuan Chen Li Ding Mingshu Mo Jing Zou Zhenze Lu Haiyan LiHaotian WuYongqiang Dai Ping-Yi Xu Zhengqi Lu

Published in: Neural plasticity (2019)

Wnt1 promoted EAAT2 expression and mediated the cytoprotective effects of astrocytes on dopaminergic cells. NF-κB might be involved in the regulation of EAAT2 by Wnt1.

Keyphrases

induced apoptosis
poor prognosis
stem cells
cell proliferation
cell cycle arrest
signaling pathway
oxidative stress
endoplasmic reticulum stress
cell death
long non coding rna
toll like receptor
inflammatory response
nuclear factor