A review on drug repurposing in COVID-19: from antiviral drugs to herbal alternatives.
Abas SezerMervisa Halilović-AlihodžićAnnissa Rachel VanwierenAdna SmajkanAmina KarićHusein DjedovićJasmin ŠutkovićPublished in: Journal, genetic engineering & biotechnology (2022)
This article summarized 11 repurposing drugs, their positive and negative health implications, along with traditional herbal alternatives, that harvest strong potential in efficient treatments options against COVID-19, with small or no significant side effects. Out of 11 repurposing drugs, four drugs are in status of emergency approval, most of them being in phase IV clinical trials. The first repurposing drug approved for clinical usage is remdesivir, whereas chloroquine and hydrochloroquine approval for emergency use was revoked by FDA for COVID-19 treatment in June 2020.