The Role of Intravitreal Anti-VEGF Agents in Rabbit Eye Model of Open-Globe Injury.

Xiao ZhaoHan HanYinting SongMei DuMengyu LiaoXue DongXiaohong WangFerenc KuhnAnnette K HoskinHeping XuHua Yan

Published in: Journal of ophthalmology (2021)

Anti-VEGF treatments after OGI significantly attenuated the upregulation of growth factors and cytokines in the vitreous and prevented intravitreal proliferation and epiretinal scar formation and thus may protect against the development of posttraumatic complications such as proliferative vitreoretinopathy (PVR).

Keyphrases

vascular endothelial growth factor
endothelial cells
signaling pathway
diabetic retinopathy
age related macular degeneration
poor prognosis
cell proliferation
minimally invasive