Undertaking multi-centre randomised controlled trials in primary care: learnings and recommendations from the PULsE-AI trial researchers.
Kevin G PollockCarissa DickersonManjit KainthSarah LawtonMichael HurstDaniel M SugrueChris ArdenD Wyn DaviesAnne-Céline MartinBelinda SandlerJason GordonUsman FarooquiDavid CliftonChristian MallenJennifer RogersNathan R HillA John CammAlexander T CohenPublished in: BMC primary care (2024)
Undertaking a formal reflection exercise following the completion of the PULsE-AI trial enabled us to review experiences encountered whilst undertaking a prospective randomised trial in primary care. In sharing our learnings, we hope to support other clinicians undertaking research in primary care to ensure that future trials are of optimal value for furthering knowledge, streamlining pathways, and benefitting patients.
Keyphrases
- primary care
- study protocol
- end stage renal disease
- blood pressure
- artificial intelligence
- clinical trial
- phase iii
- phase ii
- healthcare
- general practice
- newly diagnosed
- ejection fraction
- prognostic factors
- randomized controlled trial
- chronic kidney disease
- open label
- mental health
- high intensity
- social media
- health information
- palliative care
- current status
- machine learning
- patient reported outcomes