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Pathway-Specific Remodeling of Thalamostriatal Synapses in a Mouse Model of Parkinson's Disease.

Asami TanimuraWeixing ShenDavid WokosinDalton James Surmeier
Published in: Movement disorders : official journal of the Movement Disorder Society (2022)
Taken together, our results demonstrate that the CLN projection to the striatum undergoes a pathway-specific remodeling that could contribute to the circuit imbalance thought to drive the hypokinetic features of PD. © 2022 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.
Keyphrases
  • mouse model
  • randomized controlled trial
  • systematic review
  • magnetic resonance