Molecular characterization-based multi-omics analyses in primary liver cancer using the Japanese version of the genome atlas.

Taisuke Imamura Yukiyasu Okamura Keiichi Ohshima Katsuhiko Uesaka Teiichi Sugiura Yusuke Yamamoto Ryo Ashida Katsuhisa Ohgi Takeshi Nagashima Ken Yamaguchi

Published in: Journal of hepato-biliary-pancreatic sciences (2022)

Our dataset serves as a fundamental resource for genomic medicine for PLC in Japan and identified amplified genes located at chromosome 8q as promising therapeutic targets for the subgroup with a poor prognosis.

Keyphrases

poor prognosis
genome wide
copy number
single cell
long non coding rna
dna methylation
psychometric properties
genome wide identification
bioinformatics analysis
phase iii
gene expression
clinical trial
transcription factor
study protocol
genome wide analysis