Epigenome-wide association study of asthma and wheeze characterizes loci within HK1.
Todd M EversonHongmei ZhangGabrielle A LockettAkhilesh KaushalMelinda ForthoferSusan L EwartKimberley BurrowsCaroline L ReltonGemma C SharpA John HendersonVeeresh K PatilFaisal I RezwanS Hasan ArshadJohn W HollowayWilfried J J KarmausPublished in: Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology (2019)
We identified novel associations between asthma and wheeze with methylation at cg16658191 and the expression of HK1, which may serve as markers of, predictors of, and potentially etiologic factors involved in asthma and early life wheeze.